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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
25.45
Human Site:
S196
Identified Species:
37.33
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S196
E
E
K
E
R
T
F
S
F
C
G
T
I
E
Y
Chimpanzee
Pan troglodytes
XP_508900
901
98668
S325
E
E
K
E
R
T
F
S
F
C
G
T
I
E
Y
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
S196
E
E
K
E
R
T
F
S
F
C
G
T
I
E
Y
Dog
Lupus familis
XP_854926
772
85603
S196
E
E
K
E
R
T
F
S
F
C
G
T
I
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S196
E
E
K
E
R
T
F
S
F
C
G
T
I
E
Y
Rat
Rattus norvegicus
Q63531
735
82865
F222
H
E
K
K
A
Y
S
F
C
G
T
V
E
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
R187
S
Q
A
E
I
S
R
R
I
L
K
S
E
P
P
Chicken
Gallus gallus
Q5F3L1
789
89022
S202
D
E
N
E
R
A
Y
S
F
C
G
T
I
E
Y
Frog
Xenopus laevis
P10665
733
82620
F222
H
E
K
K
A
Y
S
F
C
G
T
V
E
Y
M
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
F227
Q
D
K
K
A
Y
S
F
C
G
T
V
E
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S424
E
N
E
Y
R
A
H
S
F
C
G
T
L
E
Y
Honey Bee
Apis mellifera
XP_395099
910
102507
R227
H
E
R
D
S
N
A
R
A
Y
S
F
C
G
T
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
V204
E
G
G
Y
S
D
V
V
D
W
W
S
L
G
V
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
E218
G
A
S
P
F
T
V
E
G
E
R
N
S
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
G178
R
V
D
Q
D
S
A
G
E
G
L
I
D
R
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
73.3
13.3
6.6
N.A.
60
6.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
26.6
86.6
20
26.6
N.A.
73.3
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
19
13
13
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
19
44
0
0
7
0
0
% C
% Asp:
7
7
7
7
7
7
0
0
7
0
0
0
7
0
0
% D
% Glu:
44
57
7
44
0
0
0
7
7
7
0
0
25
44
0
% E
% Phe:
0
0
0
0
7
0
32
19
44
0
0
7
0
0
0
% F
% Gly:
7
7
7
0
0
0
0
7
7
25
44
0
0
13
0
% G
% His:
19
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
7
0
0
7
38
0
0
% I
% Lys:
0
0
50
19
0
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
7
7
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
0
7
7
0
0
7
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
7
% P
% Gln:
7
7
0
7
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
7
0
7
0
44
0
7
13
0
0
7
0
0
7
0
% R
% Ser:
7
0
7
0
13
13
19
44
0
0
7
13
7
0
7
% S
% Thr:
0
0
0
0
0
38
0
0
0
0
19
44
0
0
7
% T
% Val:
0
7
0
0
0
0
13
7
0
0
0
19
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% W
% Tyr:
0
0
0
13
0
19
7
0
0
7
0
0
0
19
44
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _